Stem cell research could transform treatment
for some diseases |
Scientists have taken an important step forward in their bid
to use stem cells to cure serious brain diseases.
Researchers in the United States have shown these master cells
can turn into any type of brain cell in mice.
Stem cells are unique in that they can turn into any other cell
in the body.
Scientists believe they could one day be used to repair or
replace damaged cells in the body and cure a wide range of diseases.
Stem cells are seen as a potential way of reversing the effects
of Alzheimer's, Parkinson's and other similar diseases in the brain.
Laboratory tests
Dr Walter Low and colleagues at the University of Minnesota
Medical School carried out tests on mice to see if stem cells could
indeed turn into other brain cells.
They injected stem cells, taken from adult mice, into a mouse
blastocyst - a mouse in the early embryonic stage.
The result was the birth of what scientists call a chimerical
animal - an animal that shows the presence of both their own cells
and the transplanted stem cells.
Tests showed these transplanted cells had developed into nerve
cells.
Further analysis showed they had grown in areas of the brain that
are generally affected by a range of diseases, including
Parkinson's, multiple sclerosis, Huntington's and Alzheimer's.
"This research takes our findings a step further," said Dr Walter
Low, who headed the study.
The researchers are now planning to continue their research to
see if stem cells can repair damage in mice with brain diseases.
"The next step is to test what happens when the adult stem cells
are used to treat mice and rats with neurological disorders," said
Dirk Keene, one of those involved in the study.
The researchers said they hoped to finish those tests within one
year.
The findings are published in the journal Cell Transplantation.